Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400952 | 0.83 | POLB (0.74) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL23601591 | 0.83 | ALDH1A1 (0.72) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL10615422 | 0.83 | ALDH1A1 (0.72) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL13659577 | 0.78 | POLB (0.66) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6692611 | 0.78 | POLB (1.00) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL11463170 | 0.78 | POLB (1.00) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL4861809 | 0.77 | ALDH1A1 (1.00) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL392680 | 0.77 | ALDH1A1 (1.00) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL478614 | 0.77 | ALDH1A1 (1.00) | POLBALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL30216480 | 0.77 | ALDH1A1 (1.00) | POLBALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128964-A2 | ENSEMBLE-BASED VIRTUAL SCREENING REVEALS NOVEL ANTIVIRAL COMPOUNDS FOR AVIAN INFLUENZA NEURAMINIDASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-10-22 | — | — | WO | disclosed |