Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 0.82 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30216480 | 1.00 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL392680 | 1.00 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL478614 | 1.00 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7840775 | 0.98 | ALDH1A1 (0.97) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL6692611 | 0.91 | POLB (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL20246861 | 0.91 | ALDH1A1 (0.82) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL8883949 | 0.91 | ALDH1A1 (0.82) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL11463170 | 0.91 | POLB (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL6635286 | 0.89 | ALDH1A1 (0.80) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL10768539 | 0.89 | ALDH1A1 (0.80) | ALDH1A1GAAPOLBAADATL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924349-B1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | THE ROSKAMP INST (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20220081415-A1 | Amino Acid Derivatives for the Treatment of Inflammatory Diseases | THE ROSKAMP INST (US) | 2022-03-17 | — | — | US | disclosed |
| CN-113614074-A | Amino acid derivatives for the treatment of inflammatory diseases | 罗斯坎普研究所 | 2021-11-05 | — | — | CN | disclosed |
| CN-101906051-B | Synthesizing method of chiral amino indanone | UNIV CHENGDU TECHNOLOGY | 2013-01-23 | — | — | CN | disclosed |
| CN-101906051-A | Synthesizing method of chiral amino indanone | UNIV CHENGDU TECHNOLOGY | 2010-12-08 | — | — | CN | disclosed |
| US-7345035-B2 | Treatment of osteoporosis and autoimmune disease with astrogorgiadiol | UNIVERSITY OF DELAWARE (US) | 2008-03-18 | — | — | US | disclosed |
| US-20040242677-A1 | Treatment of osteoporosis and autoimmune disease with astrogorgiadiol | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-02 | — | — | US | disclosed |
| EP-0830371-B1 | IMIDAZO(1,5a]PYRIDINE DERIVED SERINE PROTEASE INHIBITORS | AKZO NOBEL NV (NL) | 2000-12-20 | — | — | EP | disclosed |
| US-5916888-A | Imidazo 1,5A!pyridine derived serine protease inhibitors | AKZO NOBEL, N.V. (NL) | 1999-06-29 | — | — | US | disclosed |
| EP-0830371-A1 | IMIDAZO 1,5a]PYRIDINE DERIVED SERINE PROTEASE INHIBITORS | Akzo Nobel N.V. (NL) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996038470-A1 | IMIDAZO[1,5a]PYRIDINE DERIVED SERINE PROTEASE INHIBITORS | AKZO NOBEL N.V. (NL) | 1996-12-05 | — | — | WO | disclosed |
| US-4099010-A | PHTHALOYL AMINO ACID HYDROXAMIC ACIDS | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4077998-A | Phthaloyl amino acid hydroxamic acids | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242677-A1 | Treatment of osteoporosis and autoimmune disease with astrogorgiadiol | SOST, PTH1R, CALCR | ALDH1A1 2535/4885GAA 3538/4885POLB 3583/4885 |
| US-20220081415-A1 | Amino Acid Derivatives for the Treatment of Inflammatory Diseases | NFKBIA, NFRKB, IKBKG | ALDH1A1 4214/4885GAA 828/4885POLB 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.