Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 0.82 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4861809 | 1.00 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL30216480 | 1.00 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL392680 | 1.00 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7840775 | 0.98 | ALDH1A1 (0.97) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL6692611 | 0.91 | POLB (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL20246861 | 0.91 | ALDH1A1 (0.82) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL8883949 | 0.91 | ALDH1A1 (0.82) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL11463170 | 0.91 | POLB (1.00) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL6635286 | 0.89 | ALDH1A1 (0.80) | ALDH1A1GAAPOLBAADATL3MBTL1 | |
| SCHEMBL10768539 | 0.89 | ALDH1A1 (0.80) | ALDH1A1GAAPOLBAADATL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624095-B | Synthesis method and application of novel chiral dihydrobenzofuran amide | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2024-09-13 | — | — | CN | claimed |
| EP-1477486-A2 | Imides as inhibitors of TNF alpha | CELGENE CORPORATION (US) | 2004-11-17 | — | — | EP | claimed |
| EP-0778827-B1 | PROCESS FOR PRODUCING A BETA-AMINO ALCOHOL | DEGUSSA (DE) | 2001-12-12 | — | — | EP | claimed |
| US-5994555-A | (4S,5S)-4-BENZYL-2-OXO-OXAZOLIDINE-5-CARBOXYLIC ACID FROM PHENYLALANINE AND PHTHALIC ANHYDRIDE | F. HOFFMAN-LAROCHE AG (CH) | 1999-11-30 | — | — | US | claimed |
| US-5859248-A | Process for the production of a β-amino alcohol | F. HOFFMAN-LA ROCHE AG (CH) | 1999-01-12 | — | — | US | claimed |
| EP-0778827-A1 | PROCESS FOR PRODUCING A BETA-AMINO ALCOHOL | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-18 | — | — | EP | claimed |
| WO-1996007642-A1 | PROCESS FOR PRODUCING A β-AMINO ALCOHOL | F. HOFFMANN-LA ROCHE AG (DE) | 1996-03-14 | — | — | WO | claimed |
| EP-0007834-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ALPHA-AMINO ACIDS AND THEIR DERIVATIVES | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1983-05-11 | — | — | EP | claimed |
| US-4275217-A | Process for the preparation of optically active α-amino acids and their derivatives | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1981-06-23 | — | — | US | claimed |
| EP-3924349-B1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | THE ROSKAMP INST (US) | 2025-06-25 | — | — | EP | disclosed |
| CN-117624095-B | Synthesis method and application of novel chiral dihydrobenzofuran amide | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2024-09-13 | — | — | CN | disclosed |
| CN-117624095-A | Synthesis method and application of novel chiral dihydrobenzofuran amide | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2024-03-01 | — | — | CN | disclosed |
| CN-112601734-B | Oximino naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-11512071-B2 | Decarboxylative cross-coupling and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2022-11-29 | — | — | US | disclosed |
| US-5698579-A | INHIBITOR OF TUMOR NECROSIS FACTOR | CELGENE CORPORATION (US) | 1997-12-16 | — | — | US | disclosed |
| US-5605914-A | INHIBITORS OF TUMOR NECROSIS FACTOR | CELGENE CORPORATION (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0706521-A1 | NOVEL IMIDES | CELGENE CORPORATION (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5463063-A | Preparation of thalidomide; inhibitor of tumor necrosis factor | CELGENE CORPORATION (US) | 1995-10-31 | — | — | US | disclosed |
| WO-1995001348-A2 | IMIDES AS INHIBITORS OF TNP ALPHA | CELGENE CORPORATION (US) | 1995-01-12 | — | — | WO | disclosed |
| US-4275217-A | Process for the preparation of optically active α-amino acids and their derivatives | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1981-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11512071-B2 | Decarboxylative cross-coupling and applications thereof | PPOX, DDO, DDC | ALDH1A1 149/4885GAA 2338/4885POLB 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.