Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.66 |
| ▸ | HK1 | P19367 | 1/20 | 0.66 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12553307 | 0.85 | MAPT (0.69) | MAPTALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL1448047 | 0.83 | ALDH1A1 (0.67) | MAPTALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL2897835 | 0.83 | MAPT (0.67) | MAPTALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL11148066 | 0.82 | MAPT (0.65) | MAPTALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL5038192 | 0.82 | MAPT (0.65) | MAPTALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL13659630 | 0.79 | MCL1 (0.70) | MAPTALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL13659611 | 0.78 | BCKDK (0.68) | MAPTALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL13659633 | 0.76 | MCL1 (0.47) | MAPTALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL13659636 | 0.75 | GPR35 (0.51) | MAPTALDH1A1HPGDSMN1; SMN2USP2 | |
| SCHEMBL8878527 | 0.75 | MAPT (0.56) | MAPTALDH1A1HPGDSMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247513-A1 | BENZOTHIOPHENE COMPOUNDS HAVING ANTIINFECTIVE ACTIVITY | GENESOFT PHARMACEUTICALS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| US-7329765-B2 | Benzothiophene compounds having antiinfective activity | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247513-A1 | BENZOTHIOPHENE COMPOUNDS HAVING ANTIINFECTIVE ACTIVITY | TOP2A, TOP1, TOP2B | MAPT 496/4885ALDH1A1 2608/4885HPGD 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.