SCHEMBL136602

SCHEMBL136602

CC1=[N+](C)c2ccccc2C1(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.49
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
LMNA P02545 4/20 0.49
HTT P42858 4/20 0.49
THRB P10828 4/20 0.49
RECQL P46063 4/20 0.49
TDP1 Q9NUW8 3/20 0.49
KDM4E B2RXH2 2/20 0.49
APEX1 P27695 1/20 0.49
MMP14 P50281 1/20 0.42
ALDH1A1 P00352 2/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
APP P05067 2/20 0.40
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PDK2 Q15119 1/20 0.32
PDK4 Q16654 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10309089 1.00 MAPT (0.49) MAPTMEN1KMT2ALMNAHTT
Iodide SCHEMBL29099250 0.98 MAPT (0.47) MAPTMEN1KMT2ALMNAHTT
Iodide SCHEMBL29450242 0.98 MAPT (0.47) MAPTMEN1KMT2ALMNAHTT
SCHEMBL6853538 0.98 MAPT (0.47) MAPTMEN1KMT2ALMNAHTT
Iodide SCHEMBL29362949 0.98 MAPT (0.47) MAPTMEN1KMT2ALMNAHTT
Bromide SCHEMBL4604526 0.98 MAPT (0.47) MAPTMEN1KMT2ALMNAHTT
Hydrochloric Acid SCHEMBL4604209 0.98 MAPT (0.47) MAPTMEN1KMT2ALMNAHTT
Iodide SCHEMBL1865228 0.98 MAPT (0.47) MAPTMEN1KMT2ALMNAHTT
SCHEMBL4604770 0.92 MAPT (0.44) MAPTMEN1KMT2ALMNAHTT
Sulfuric Acid SCHEMBL4604131 0.89 MAPT (0.45) MAPTMEN1KMT2ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717169-B N, N-diphenylamino-modified beta-carboline indolium salt, preparation method and application 南通大学 2022-05-17 CN claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
US-8034125-B2 Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition L'OREAL S.A. (FR) 2011-10-11 US claimed
EP-2205681-B1 DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION OREAL (FR) 2011-08-31 EP claimed
US-20110016642-A1 DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION L'OREAL S.A. (FR) 2011-01-27 US claimed
EP-2205681-A1 DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION L'Oreal (FR) 2010-07-14 EP claimed
US-7678156-B2 Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein HENKEL AG & CO. KGAA (DE) 2010-03-16 US claimed
US-20100037909-A1 SUBSTANCES FOR DYEING KERATINOUS FIBERS HENKEL AG & CO. KGAA (DE) 2010-02-18 US claimed
WO-2009040354-A1 DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION L'OREAL (FR) 2009-04-02 WO claimed
EP-1796627-B1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL AG & CO KGAA (DE) 2009-03-04 EP claimed
EP-1535601-A1 Use of ninhydrin derivatives in colouring L'OREAL (FR) 2005-06-01 EP claimed
EP-1530963-A1 Use of ninhydrin derivatives in colouring L'OREAL (FR) 2005-05-18 EP claimed
EP-1194116-B1 AGENT FOR DYEING FIBRES CONTAINING KERATIN HENKEL KGAA (DE) 2005-05-04 EP claimed
EP-1502580-A1 Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles L'OREAL (FR) 2005-02-02 EP claimed
EP-1500387-A1 Use of ninhydrin derivatives for dyeing L'OREAL (FR) 2005-01-26 EP claimed
EP-1037586-B1 UTILIZATION OF ONIUM ALDEHYDES AND ONIUM KETONES FOR DYING FIBERS CONTAINING KERATIN HENKEL KGAA (DE) 2004-12-22 EP claimed
EP-1432388-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
EP-1139990-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2004-05-06 EP claimed
WO-2003030847-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1139988-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2002-09-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110016642-A1 DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION KRT18, SQOR, TST MAPT 1485/4885MEN1 4336/4885KMT2A 2387/4885
US-20100037909-A1 SUBSTANCES FOR DYEING KERATINOUS FIBERS KRT18, H1-10, COL1A1 MAPT 446/4885MEN1 3588/4885KMT2A 1767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.