Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064053 | 0.83 | MEN1 (0.48) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL14192857 | 0.83 | ABCB1 (0.54) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL14192859 | 0.82 | ABCB1 (0.44) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL14597230 | 0.77 | P2RY6 (0.48) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL13577577 | 0.77 | P2RY6 (0.48) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL15462762 | 0.77 | MEN1 (0.43) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL14192841 | 0.77 | MEN1 (0.51) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL15704737 | 0.77 | MEN1 (0.41) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL13577578 | 0.76 | P2RY6 (0.44) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL14077551 | 0.76 | MEN1 (0.40) | MEN1KMT2ABLMTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263868-A1 | Nucleotide Compositions Comprising Photocleavable Markers And Methods Of Preparation Thereof | AMBERGEN, INC. | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263868-A1 | Nucleotide Compositions Comprising Photocleavable Markers And Methods Of Preparation Thereof | POLN, NT5C3B, RNGTT | MEN1 3335/4885KMT2A 3328/4885BLM 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.