Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | LCAT | P04180 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | USP14 | P54578 | 2/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660458 | 0.82 | DRD1 (0.35) | SPR | |
| SCHEMBL13985423 | 0.81 | PDE4B (0.34) | PDE4BPDE4DLCATDPP4USP14 | |
| SCHEMBL4755607 | 0.81 | PDE4B (0.34) | PDE4BPDE4DLCATDPP4USP14 | |
| SCHEMBL13660312 | 0.81 | PDE4B (0.43) | PDE4BPDE4DPDE4ALCATUSP14 | |
| SCHEMBL13660450 | 0.78 | CTSL (0.35) | PDE4BPDE4DPDE4ALCATDPP4 | |
| SCHEMBL3169620 | 0.73 | DRD1 (0.37) | PDE4ASPR | |
| SCHEMBL3169614 | 0.73 | DRD1 (0.37) | PDE4ASPR | |
| SCHEMBL3169708 | 0.73 | PDE4B (0.44) | PDE4BPDE4DPDE4ALCATUSP14 | |
| SCHEMBL3169713 | 0.73 | PDE4B (0.44) | PDE4BPDE4DPDE4ALCATUSP14 | |
| SCHEMBL13660308 | 0.73 | CHRNB2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009121036-A2 | SUBSTITUTED ARYL PYRIMIDINONE DERIVATIVES | NEUROGEN CORPORATION (US) | 2009-10-01 | — | — | WO | disclosed |