Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 6/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003885 | 0.90 | GPR119 (0.42) | GPR119POLB | |
| SCHEMBL13660399 | 0.82 | UTS2R (0.43) | GPR119KITHRH3UTS2R | |
| SCHEMBL13660325 | 0.79 | DRD2 (0.43) | GPR119KITTYRO3AXLHRH3 | |
| SCHEMBL13660402 | 0.76 | GPR119 (0.38) | GPR119KITTYRO3AXLHRH3 | |
| SCHEMBL13660401 | 0.76 | KIT (0.38) | GPR119KITHRH3 | |
| SCHEMBL12239171 | 0.74 | GPR119 (0.43) | GPR119 | |
| SCHEMBL12239152 | 0.74 | ADRB2 (0.43) | GPR119HRH3POLBCHEK1 | |
| SCHEMBL12239172 | 0.74 | SMN1; SMN2 (0.43) | GPR119HRH3POLBUTS2R | |
| SCHEMBL1006217 | 0.73 | GPR119 (0.47) | GPR119 | |
| SCHEMBL1007705 | 0.72 | GPR119 (0.44) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126535-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-10-15 | — | — | WO | disclosed |