Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660308 | 0.90 | CHRNB2 (0.31) | — | |
| SCHEMBL13660458 | 0.85 | DRD1 (0.35) | POLBDRD1DRD5PI4KBGRM1 | |
| SCHEMBL3169614 | 0.80 | DRD1 (0.37) | POLBDRD1DRD5PI4KBGRM1 | |
| SCHEMBL3169620 | 0.80 | DRD1 (0.37) | POLBDRD1DRD5PI4KBGRM1 | |
| SCHEMBL13660412 | 0.79 | HRH3 (0.40) | DRD1DRD5 | |
| SCHEMBL13985230 | 0.78 | DRD1 (0.39) | POLBDRD1DRD5GRM1 | |
| SCHEMBL4753340 | 0.78 | DRD1 (0.39) | POLBDRD1DRD5GRM1 | |
| SCHEMBL4514625 | 0.76 | DRD1 (0.38) | POLBDRD1DRD5GRM1GRM5 | |
| SCHEMBL13985522 | 0.73 | CRHR1 (0.41) | POLBDRD1DRD5 | |
| SCHEMBL4756481 | 0.73 | CRHR1 (0.41) | POLBDRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009121036-A2 | SUBSTITUTED ARYL PYRIMIDINONE DERIVATIVES | NEUROGEN CORPORATION (US) | 2009-10-01 | — | — | WO | disclosed |