Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCL5 | P13501 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660770 | 0.88 | CCR5 (0.33) | CCL5CCR5BDKRB1TSHRHIF1A | |
| SCHEMBL4298918 | 0.85 | RORC (0.34) | BDKRB1 | |
| SCHEMBL4292696 | 0.73 | BDKRB1 (0.37) | CCR5BDKRB1 | |
| SCHEMBL4294660 | 0.67 | NPC1 (0.33) | CCR5 | |
| SCHEMBL4295145 | 0.66 | BDKRB1 (0.36) | BDKRB1 | |
| SCHEMBL4299091 | 0.66 | ALDH1A1 (0.35) | CCR5 | |
| SCHEMBL3313157 | 0.66 | RORC (0.36) | BDKRB1TSHRHIF1A | |
| SCHEMBL701988 | 0.65 | BDKRB1 (0.39) | CCR5BDKRB1 | |
| SCHEMBL4295264 | 0.65 | CCR1 (0.34) | CCR5 | |
| SCHEMBL4300839 | 0.64 | BDKRB1 (0.41) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264400-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264400-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, TRPV1 | CCL5 2255/4885CCR5 1354/4885BDKRB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.