Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | CCR5 | P51681 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660806 | 0.89 | OPRM1 (0.47) | OPRM1CCR5LMNASIGMAR1BCHE | |
| SCHEMBL13661596 | 0.85 | SIGMAR1 (0.46) | KDM4ESIGMAR1NPC1RAB9A | |
| SCHEMBL13660815 | 0.83 | HTR7 (0.44) | CCR5SIGMAR1 | |
| SCHEMBL13660817 | 0.79 | KDM4E (0.52) | KDM4EMEN1KMT2ASIGMAR1BCHE | |
| SCHEMBL13661448 | 0.79 | SIGMAR1 (0.46) | CCR5KDM4ESIGMAR1NPC1RAB9A | |
| SCHEMBL13661141 | 0.78 | NPC1 (0.49) | KDM4EMEN1KMT2ASIGMAR1NPC1 | |
| SCHEMBL18594775 | 0.77 | CCR6 (0.52) | LMNATSHRKMT2A | |
| SCHEMBL16665613 | 0.76 | ALDH1A1 (0.58) | MEN1LMNATSHRKMT2ANPC1 | |
| SCHEMBL13661589 | 0.76 | CCR6 (0.51) | SIGMAR1 | |
| SCHEMBL13661335 | 0.76 | CCR6 (0.51) | OPRM1KDM4EMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |