SCHEMBL42348

SCHEMBL42348

C1CCN(CCC2CCNCC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 4/20 0.49
CYP1A2 P05177 1/20 0.46
RAD52 P43351 1/20 0.42
CHRM5 P08912 1/20 0.40
ADRA2C P18825 1/20 0.40
GNAI3 P08754 3/20 0.40
GNAI1 P63096 3/20 0.40
CXCR4 P61073 3/20 0.39
HRH3 Q9Y5N1 1/20 0.39
NPY1R P25929 1/20 0.35
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
F2R P25116 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4424002 0.98 GNAO1 (0.51) GNAO1CYP1A2RAD52CHRM5ADRA2C
SCHEMBL640737 0.98 GNAO1 (0.50) GNAO1CYP1A2RAD52CHRM5ADRA2C
SCHEMBL13660827 0.96 GNAO1 (0.46) GNAO1CYP1A2RAD52CHRM5ADRA2C
Hydrochloric Acid SCHEMBL6150599 0.96 GNAO1 (0.53) GNAO1CYP1A2RAD52CHRM5ADRA2C
SCHEMBL13661478 0.94 GNAO1 (0.45) GNAO1CYP1A2RAD52CHRM5ADRA2C
SCHEMBL3440711 0.94 GNAO1 (0.50) GNAO1CYP1A2RAD52GNAI3GNAI1
SCHEMBL13660823 0.89 CHRM5 (0.50) GNAO1CYP1A2RAD52CHRM5ADRA2C
SCHEMBL7122133 0.88 GNAO1 (0.54) GNAO1RAD52GNAI3GNAI1CXCR4
SCHEMBL9824369 0.88 GNAO1 (0.54) GNAO1RAD52GNAI3GNAI1CXCR4
SCHEMBL7462427 0.88 CYP1A2 (0.43) GNAO1CYP1A2RAD52CHRM5ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3401370-A1 AMINO (METH)ACRYLATES Allnex Belgium S.A. (BE) 2018-11-14 EP claimed
WO-2026102212-A1 MACROCYCLIC MCL-1 INHIBITORS VANDERBILT UNIVERSITY (US) 2026-05-15 WO disclosed
US-12528948-B2 Amino (meth)acrylates ALLNEX BELGIUM S.A. (BE) 2026-01-20 US disclosed
CN-119823124-A Compounds for targeted degradation of BRD9 C4医药公司 2025-04-15 CN disclosed
CN-115279370-B Compounds for targeted degradation of BRD9 C4医药公司 2025-01-10 CN disclosed
CN-111295373-B Compositions and methods for treating brain injury 阿泽凡药物公司 2024-12-10 CN disclosed
US-20240115553-A1 COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY AZEVAN PHARMACEUTICALS, INC. (US) 2024-04-11 US disclosed
US-20230322761-A1 DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE BEONE MEDICINES I GMBH (CH) 2023-10-12 US disclosed
CN-116327950-A Use of a composition for the treatment of neuropsychiatric symptoms of neurodegenerative diseases 阿泽范药品公司 2023-06-27 CN disclosed
CN-116285486-A Radiation-curable amino (methyl) acrylate resin, ink composition and application thereof 长兴特殊材料(珠海)有限公司 2023-06-23 CN disclosed
EP-0720602-A1 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS KNOLL AG (DE) 1996-07-10 EP disclosed
WO-1995008535-A1 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS KNOLL AG (DE) 1995-03-30 WO disclosed
EP-0306698-B1 CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION, AND MEDICAMENTS CONTAINING THESE COMPOUNDS Dr. Karl Thomae GmbH (DE) 1992-03-25 EP disclosed
EP-0273239-B1 CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1991-03-06 EP disclosed
US-4931436-A BRADYCARDIAL AGENTS DR. KARL THOMAE GMBH (DE) 1990-06-05 US disclosed
US-4873236-A BRADYCARDIAL AGENTS DR. KARL THOMAE GMBH (DE) 1989-10-10 US disclosed
EP-0306698-A1 Condensed diazepinones, processes for their preparation, and medicaments containing these compounds Dr. Karl Thomae GmbH (DE) 1989-03-15 EP disclosed
EP-0273239-A1 Condensed diazepinones, processes for their preparation and medicaments containing them Dr. Karl Thomae GmbH (DE) 1988-07-06 EP disclosed
US-4345071-A AZIDOALKYL-HETEROCYCLIC AMIDINE INTERMEDIATES LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) 1982-08-17 US disclosed
US-4229443-A Derivatives of penicillanic acid LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) 1980-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115553-A1 COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY FABP7, PYGB, CHAT GNAO1 2970/4885CYP1A2 2732/4885RAD52 2776/4885
US-20230322761-A1 DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE BTK, CBL, LYN GNAO1 2590/4885CYP1A2 4579/4885RAD52 1024/4885
US-12528948-B2 Amino (meth)acrylates MAT2B, MAT1A, MMAB GNAO1 2838/4885CYP1A2 1516/4885RAD52 221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.