Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504656 | 0.94 | GBA1 (0.44) | GBA1 | |
| Hydrochloric Acid SCHEMBL4387922 | 0.93 | GBA1 (0.42) | GBA1 | |
| SCHEMBL16254938 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4ECHRM5ADRA2CMAPT | |
| SCHEMBL14828674 | 0.84 | CHRM5 (0.52) | ALDH1A1KDM4ECHRM5ADRA2CACHE | |
| SCHEMBL3713667 | 0.84 | SLC6A1 (0.35) | GBA1 | |
| SCHEMBL3005090 | 0.84 | SLC6A1 (0.35) | GBA1 | |
| SCHEMBL3005092 | 0.84 | SLC6A1 (0.35) | GBA1 | |
| SCHEMBL10998848 | 0.82 | ACHE (0.47) | GBA1ALDH1A1KDM4ECHRM5ADRA2C | |
| SCHEMBL13544153 | 0.80 | ACHE (0.50) | GBA1ALDH1A1KDM4ECHRM5ADRA2C | |
| SCHEMBL22852502 | 0.80 | HRH3 (0.42) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |