SCHEMBL13664002

SCHEMBL13664002

Cc1cn([C@@H]2C=C(CO)[C@H](O)C2)c(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.49
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
ALB P02768 1/20 0.46
POLB P06746 1/20 0.46
ADRA1A P35348 1/20 0.46
BLM P54132 1/20 0.46
TYMP P19971 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13664000 0.76 SLC28A1 (0.48)
SCHEMBL13667652 0.75 ALDH1A1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL12280514 0.75 ALDH1A1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL8660778 0.73 TK1 (0.50) TK1ALDH1A1LMNAALBPOLB
SCHEMBL9149865 0.73 TK1 (0.50) TK1ALDH1A1LMNAALBPOLB
SCHEMBL13664020 0.73 ALDH1A1 (0.45) TK1ALDH1A1LMNAALBPOLB
SCHEMBL14544398 0.73 ALDH1A1 (0.45) TK1ALDH1A1LMNAALBPOLB
SCHEMBL9310153 0.72 TK1 (0.60) TK1ALDH1A1LMNAALBPOLB
SCHEMBL30807817 0.72 ALDH1A1 (0.53) TK1ALDH1A1LMNAALBPOLB
SCHEMBL14124039 0.72 TK1 (0.50) TK1ALDH1A1LMNAALBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090270431-A1 Cyclopentenol Nucleoside Compounds Intermediates for their Synthesis and Methods of Treating Viral Infections THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) 2009-10-29 US disclosed
WO-2007047793-A2 CYCLOPENTENOL NUCLEOSIDE COMPOUNDS, INTERMEDIATES FOR THEIR SYNTHESIS AND METHODS OF TREATING VIRAL INFECTIONS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270431-A1 Cyclopentenol Nucleoside Compounds Intermediates for their Synthesis and Methods of Treating Viral Infections REV1, NSUN2, ORC3 TK1 501/4885ALDH1A1 1749/4885LMNA 954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.