Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | HCK | P08631 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533679 | 0.87 | PIK3CD (0.43) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL2002026 | 0.79 | BRD9 (0.42) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL8533712 | 0.79 | PIK3CD (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL3834511 | 0.78 | HTR6 (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL13664698 | 0.75 | MEN1 (0.42) | NR1H2MEN1KMT2AESR2USP30 | |
| SCHEMBL14894490 | 0.75 | LMNA (0.43) | NR1H2ESR2MAPTALDH1A1LMNA | |
| SCHEMBL948951 | 0.74 | HTR6 (0.47) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL18291495 | 0.74 | NR1H2 (0.42) | NR1H2MEN1KMT2AESR2MAPT | |
| SCHEMBL3839678 | 0.73 | HPGD (0.50) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL26979735 | 0.72 | C5AR1 (0.45) | NR1H2ESR2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |