Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.63 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664867 | 0.87 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3HTR3AHTR3E | |
| SCHEMBL13664706 | 0.83 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3HTR3AHTR3E | |
| SCHEMBL5480292 | 0.81 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3HTR3AHTR3E | |
| SCHEMBL27852746 | 0.80 | ALDH1A1 (0.54) | SLC6A2SLC6A4SLC6A3HSP90AA1HTR6 | |
| SCHEMBL13664863 | 0.78 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17751337 | 0.77 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR3AHTR3E | |
| SCHEMBL13664888 | 0.75 | SLC6A2 (0.79) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL28282299 | 0.75 | ALDH1A1 (0.53) | SLC6A2SLC6A4SLC6A3HTR6ALDH1A1 | |
| SCHEMBL13664737 | 0.74 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL14894749 | 0.74 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR3AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |