Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.79 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.79 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664863 | 0.88 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13664684 | 0.84 | SLC6A2 (0.91) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26920629 | 0.80 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3RAD51TSHR | |
| SCHEMBL26774776 | 0.77 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3HSD11B1 | |
| SCHEMBL13665288 | 0.75 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13664717 | 0.75 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL5480292 | 0.73 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL13664737 | 0.73 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13664710 | 0.72 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL13664702 | 0.72 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |