Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664717 | 0.83 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL1665546 | 0.79 | ADRB1 (0.56) | SLC6A2SLC6A4SLC6A3HTR1AHTR1D | |
| SCHEMBL1663489 | 0.78 | ADRB1 (0.59) | SLC6A2SLC6A4SLC6A3HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL1584077 | 0.77 | ADRB1 (0.54) | SLC6A2SLC6A4SLC6A3HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL1584087 | 0.77 | ADRB1 (0.57) | SLC6A2SLC6A4SLC6A3HTR1AHTR2A | |
| SCHEMBL13664863 | 0.73 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3ADRB1L3MBTL1 | |
| SCHEMBL13664737 | 0.73 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3TP53KMT2A | |
| SCHEMBL13362047 | 0.71 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL13664867 | 0.71 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL13664888 | 0.71 | SLC6A2 (0.79) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |