Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.62 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664713 | 0.74 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL13664741 | 0.73 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3ACACA | |
| SCHEMBL11818068 | 0.68 | KMT2A (0.44) | BPTFTSHRMEN1GAAKMT2A | |
| SCHEMBL13664745 | 0.67 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3MEN1GAA | |
| SCHEMBL8306961 | 0.66 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10192199 | 0.65 | IDH1 (0.43) | TSHR | |
| SCHEMBL13664856 | 0.64 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13664737 | 0.64 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL1583560 | 0.63 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3ARBPTF | |
| SCHEMBL26667207 | 0.63 | MGLL (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |