Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985382 | 0.79 | RECQL (0.54) | SLC6A2SLC6A4SLC6A3RECQLHCAR1 | |
| SCHEMBL13664823 | 0.75 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3RECQLHCAR1 | |
| Acetic Acid SCHEMBL2981956 | 0.74 | RECQL (0.48) | RECQLHCAR1P2RX7MEN1KMT2A | |
| SCHEMBL292679 | 0.67 | HSD11B1 (0.46) | RECQLMGLL | |
| SCHEMBL13664738 | 0.67 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL13664713 | 0.66 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3RECQLMEN1 | |
| SCHEMBL293635 | 0.65 | RECQL (0.40) | RECQLHCAR1P2RX7MEN1KMT2A | |
| SCHEMBL30910322 | 0.63 | NPC1 (0.54) | RECQLP2RX7MEN1KMT2AGAA | |
| SCHEMBL9172497 | 0.63 | MGLL (0.66) | RECQLHCAR1GAAALOX15MGLL | |
| SCHEMBL15761176 | 0.61 | RECQL (0.45) | RECQLHCAR1P2RX7GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |