Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770189 | 0.76 | L3MBTL1 (0.49) | SLC6A2SLC6A4SLC6A3L3MBTL1KMT2A | |
| SCHEMBL13664738 | 0.74 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL25313921 | 0.69 | ACACB (0.51) | NPC1RAB9AITGB3ITGA2BMAPT | |
| Hydrochloric Acid SCHEMBL25314024 | 0.68 | ACACB (0.50) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL14003534 | 0.67 | L3MBTL1 (1.00) | L3MBTL1KMT2AADAM17NPC1RAB9A | |
| SCHEMBL16644311 | 0.67 | ALDH1A1 (0.59) | ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL25676620 | 0.66 | ALDH1A1 (0.59) | L3MBTL1KMT2AADAM17NPC1RAB9A | |
| SCHEMBL16637329 | 0.66 | OPRM1 (0.41) | L3MBTL1RAB9AITGB3ITGA2BMAPT | |
| SCHEMBL10127533 | 0.65 | ACACA (0.54) | ITGB3ITGA2BMAPTALDH1A1OPRM1 | |
| SCHEMBL26475517 | 0.65 | CRBN (0.63) | L3MBTL1KMT2AADAM17NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |