Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.42 |
| ▸ | HTR3B | O95264 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31537000 | 0.86 | SLC6A4 (0.51) | MAPTUSP2HTR2CHTR2AHTR2B | |
| SCHEMBL13664710 | 0.78 | SLC6A2 (0.63) | MAPTUSP2ADRA1BHTR1ASLC6A4 | |
| SCHEMBL30511075 | 0.75 | ADRB1 (0.63) | USP2HTR2CHTR2AHTR2BADRA1B | |
| SCHEMBL4328782 | 0.75 | ADRB1 (0.63) | USP2HTR2CHTR2AHTR2BADRA1B | |
| Hydrochloric Acid SCHEMBL29832037 | 0.74 | ADRB1 (0.61) | USP2HTR2CHTR2AHTR2BHTR3E | |
| Hydrochloric Acid SCHEMBL6965349 | 0.74 | ADRB1 (0.61) | USP2HTR2CHTR2AHTR2BHTR3E | |
| Hydrochloric Acid SCHEMBL3649806 | 0.74 | ADRB1 (0.61) | USP2HTR2CHTR2AHTR2BHTR3E | |
| SCHEMBL13664744 | 0.74 | SLC6A2 (0.48) | USP2ADRB1SLC6A4HTR6F10 | |
| SCHEMBL9982890 | 0.72 | NPSR1 (0.43) | MAPTHTR2CHTR2AHTR3EHTR3B | |
| SCHEMBL13664714 | 0.72 | SLC6A2 (0.49) | MAPTADRB1SLC6A4HTR6F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |