Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806569 | 0.82 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3RAD51 | |
| SCHEMBL13664714 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3ADRB1HTR6 | |
| SCHEMBL31662970 | 0.79 | RAD51 (0.44) | SLC6A2SLC6A4SLC6A3RAD51CYP11B2 | |
| SCHEMBL13665288 | 0.78 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3ADRB1HTR6 | |
| SCHEMBL1186845 | 0.77 | ADRB1 (0.71) | SLC6A4ADRB1HTR6 | |
| SCHEMBL30609657 | 0.77 | ADRB1 (0.71) | SLC6A4ADRB1HTR6 | |
| SCHEMBL13664742 | 0.74 | MAPT (0.50) | SLC6A2SLC6A4SLC6A3ADRB1HTR6 | |
| SCHEMBL1583560 | 0.73 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3RAD51F10 | |
| SCHEMBL8257562 | 0.72 | HTR6 (0.53) | SLC6A2SLC6A4SLC6A3HTR6F10 | |
| Hydrochloric Acid SCHEMBL1583620 | 0.72 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |