Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816315 | 0.81 | ALDH1A1 (0.56) | SLC6A2SLC6A4SLC6A3PKMALDH1A1 | |
| SCHEMBL13664744 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ADRB1F10 | |
| SCHEMBL13665288 | 0.79 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3ADRB1HTR6 | |
| SCHEMBL2984679 | 0.76 | ADRB1 (0.73) | SLC6A4ALDH1A1SMN1; SMN2KMT2AADRB1 | |
| SCHEMBL18291654 | 0.73 | PIM1 (0.43) | SLC6A2ALDH1A1HPGDADRB1F10 | |
| SCHEMBL9819263 | 0.73 | PKM (0.50) | SLC6A2SLC6A4PKMALDH1A1HPGD | |
| SCHEMBL26774776 | 0.72 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3PKMADRB1 | |
| SCHEMBL13664742 | 0.72 | MAPT (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1KMT2A | |
| SCHEMBL21533600 | 0.71 | ADRB1 (0.65) | SLC6A4ALDH1A1SMN1; SMN2KMT2AADRB1 | |
| SCHEMBL7814371 | 0.71 | ALDH1A1 (0.58) | SLC6A2SLC6A4SLC6A3PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |