SCHEMBL948951

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8533712	0.90	PIK3CD (0.44)	HTR6MAPTALDH1A1LMNAABL1
	SCHEMBL3834511	0.89	HTR6 (0.44)	HTR6MAPTALDH1A1LMNAABL1
	SCHEMBL17183999	0.88	SUV39H2 (0.40)	HTR6MAPTALDH1A1LMNAABL1
	SCHEMBL15758673	0.81	SUV39H2 (0.38)	HTR6MAPTALDH1A1LMNAABL1
	SCHEMBL3049873	0.81	HPGD (0.51)	MAPTALDH1A1KDRMAPK1MEN1
	SCHEMBL8857983	0.81	MAPT (0.53)	HTR6SMN1; SMN2MAPTALDH1A1LMNA
	SCHEMBL30974281	0.80	MEN1 (0.46)	KDM4ENPC1RAB9ASMN1; SMN2MAPT
	SCHEMBL13291552	0.80	KDM4E (0.45)	HTR6KDM4ENPC1RAB9ASMN1; SMN2
	SCHEMBL27423824	0.80	MEN1 (0.46)	KDM4ENPC1RAB9ASMN1; SMN2MAPT
	SCHEMBL5351570	0.79	THRB (0.49)	KDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.