Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13882615 | 0.92 | TP53 (0.53) | PTGS2ALDH1A1SRD5A2HDAC1HDAC2 | |
| SCHEMBL31324088 | 0.85 | TRPA1 (0.62) | PTGS2SRD5A2HDAC1HDAC2TP53 | |
| SCHEMBL29000782 | 0.84 | MEN1 (0.59) | PTGS2ALDH1A1HDAC1HDAC2TP53 | |
| SCHEMBL13449659 | 0.82 | TP53 (0.52) | PTGS2ALDH1A1SRD5A2HDAC1HDAC2 | |
| SCHEMBL28083230 | 0.82 | TP53 (0.52) | PTGS2ALDH1A1SRD5A2HDAC1HDAC2 | |
| SCHEMBL27937341 | 0.82 | MAPK1 (0.54) | PTGS2ALDH1A1SRD5A2TDP1L3MBTL1 | |
| Acetophenone SCHEMBL14860336 | 0.81 | PTGS2 (0.54) | PTGS2ALDH1A1HDAC1HDAC2TDP1 | |
| SCHEMBL28259495 | 0.81 | PTGS2 (0.47) | PTGS2ALDH1A1SRD5A2HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL28856167 | 0.80 | TP53 (0.50) | PTGS2ALDH1A1SRD5A2HDAC1HDAC2 | |
| Acetophenone SCHEMBL29127417 | 0.79 | PTGS2 (0.51) | PTGS2ALDH1A1HDAC1HDAC2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607300-B1 | PROCESS FOR HYDROGENATION OF ORGANIC COMPOUNDS USING HYDROGEN OR HEAVY HYDROGEN | SHIONO CHEMICAL CO LTD (JP) | 2020-05-13 | — | — | EP | disclosed |
| US-9676622-B2 | Process for producing hydrogen or heavy hydrogens, and hydrogenation (protiation, deuteration or tritiation) of organic compounds using same | SHIONO CHEMICAL CO., LTD. (JP) | 2017-06-13 | — | — | US | disclosed |
| US-9676622-B2 | Process for producing hydrogen or heavy hydrogens, and hydrogenation (protiation, deuteration or tritiation) of organic compounds using same | SHIONO CHEMICAL CO., LTD. (JP) | 2017-06-13 | — | — | US | disclosed |
| US-9676622-B2 | Process for producing hydrogen or heavy hydrogens, and hydrogenation (protiation, deuteration or tritiation) of organic compounds using same | SHIONO CHEMICAL CO., LTD. (JP) | 2017-06-13 | — | — | US | disclosed |
| US-20140363369-A1 | PROCESS FOR PRODUCING HYDROGEN OR HEAVY HYDROGENS, AND HYDROGENATION (PROTIATION, DEUTERATION OR TRITIATION) OF ORGANIC COMPOUNDS USING SAME | SHIONO CHEMICAL CO., LTD. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-20140363369-A1 | PROCESS FOR PRODUCING HYDROGEN OR HEAVY HYDROGENS, AND HYDROGENATION (PROTIATION, DEUTERATION OR TRITIATION) OF ORGANIC COMPOUNDS USING SAME | SHIONO CHEMICAL CO., LTD. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-20140363369-A1 | PROCESS FOR PRODUCING HYDROGEN OR HEAVY HYDROGENS, AND HYDROGENATION (PROTIATION, DEUTERATION OR TRITIATION) OF ORGANIC COMPOUNDS USING SAME | SHIONO CHEMICAL CO., LTD. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-8871980-B2 | Process for producing hydrogen or heavy hydrogens, and hydrogenation (protiation, deuteration or tritiation) of organic compounds using same | SHIONO CHEMICAL CO., LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| US-8871980-B2 | Process for producing hydrogen or heavy hydrogens, and hydrogenation (protiation, deuteration or tritiation) of organic compounds using same | SHIONO CHEMICAL CO., LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| EP-2607300-A1 | PROCESS FOR PRODUCING HYDROGEN OR HEAVY HYDROGENS, AND HYDROGENATION (PROTIATION, DEUTERATION OR TRITIATION) OF ORGANIC COMPOUNDS USING SAME | Shiono Chemical Co., Ltd. (JP) | 2013-06-26 | — | — | EP | disclosed |
| US-20130150623-A1 | PROCESS FOR PRODUCING HYDROGEN OR HEAVY HYDROGENS, AND HYDROGENATION (PROTIATION, DEUTERATION OR TRITIATION) OF ORGANIC COMPOUNDS USING SAME | SHIONO CHEMICAL CO., LTD. (JP) | 2013-06-13 | — | — | US | disclosed |
| US-20130150623-A1 | PROCESS FOR PRODUCING HYDROGEN OR HEAVY HYDROGENS, AND HYDROGENATION (PROTIATION, DEUTERATION OR TRITIATION) OF ORGANIC COMPOUNDS USING SAME | SHIONO CHEMICAL CO., LTD. (JP) | 2013-06-13 | — | — | US | disclosed |
| US-20110038890-A1 | Cellular And Viral Inactivation | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2011-02-17 | — | — | US | disclosed |
| US-20110038890-A1 | Cellular And Viral Inactivation | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2011-02-17 | — | — | US | disclosed |
| WO-2009131606-A2 | VIRAL INACTIVATION USING CROSSLINKERS AND DETERGENTS | BELANGER JULIE M (US) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110038890-A1 | Cellular And Viral Inactivation | PDIA5, HAVCR2, MAVS | PTGS2 3982/4885ALDH1A1 2690/4885SRD5A2 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.