Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801356 | 0.92 | SMN1; SMN2 (0.53) | ALDH1A1EPHX1HTTLMNAKDM4E | |
| SCHEMBL801355 | 0.81 | EPHX2 (0.48) | ALDH1A1EPHX1HTTSMN1; SMN2HDAC1 | |
| SCHEMBL1104199 | 0.81 | MAPT (0.46) | ALDH1A1KDM4ESMN1; SMN2NPSR1MAPT | |
| SCHEMBL14983567 | 0.80 | SMN1; SMN2 (0.57) | ALDH1A1EPHX1HTTLMNAKDM4E | |
| SCHEMBL2742140 | 0.79 | EPHX2 (0.49) | ALDH1A1EPHX1NPSR1MAPTCYP1A2 | |
| SCHEMBL19822027 | 0.78 | EPHX1 (0.38) | EPHX1MAPT | |
| SCHEMBL10595824 | 0.78 | LMNA (0.68) | ALDH1A1EPHX1HTTLMNAKDM4E | |
| SCHEMBL13223590 | 0.78 | EPHX1 (0.47) | ALDH1A1EPHX1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL12126301 | 0.77 | EPHX2 (0.45) | ALDH1A1SMN1; SMN2HDAC1MAPTKMT2A | |
| SCHEMBL18364395 | 0.77 | ALDH1A1 (0.63) | ALDH1A1EPHX1HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090246693-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |