SCHEMBL13668477

SCHEMBL13668477

CSc1ccc(C)cc1Cc1ccc(C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
IDO1 P14902 1/20 0.35
HPGD P15428 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
GAA P10253 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
HSD17B10 Q99714 1/20 0.35
AMY1A P0DUB6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13925959 0.91 SLC6A4 (0.46) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL18508629 0.78 MAPT (0.39) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL11064216 0.76 ALOX15 (0.42) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL13616190 0.76 MAPT (0.38) PDE3BPDE3ANPC1RAB9AMAPT
SCHEMBL31158270 0.75 TAAR1 (0.52) PDE3BPDE3ANPC1RAB9ATSHR
SCHEMBL10675819 0.75 TAAR1 (0.52) PDE3BPDE3ANPC1RAB9ATSHR
Hydrochloric Acid SCHEMBL1013629 0.74 SLC6A4 (0.47) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL25612771 0.74 MAPT (0.40) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL12736251 0.73 SLC6A4 (0.36) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL5551682 0.73 TAAR1 (0.54) PDE3BPDE3ANPC1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7601449-B2 Sulfonated poly(phenylene sulfide) films as polyelectrolyte membranes GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-10-13 US disclosed
US-7432339-B2 Inferred water analysis in polyphenylene sulfide production CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-10-07 US disclosed
US-20080103271-A1 Inferred Water Analysis in Polyphenylene Sulfide Production CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2008-05-01 US disclosed
US-7312300-B2 Inferred water analysis in polyphenylene sulfide production CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-12-25 US disclosed
US-7205354-B2 Resin-made mechanical element with excellent heat resistance and dimensional precision for optical disk drive ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-04-17 US disclosed