Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | RECQL | P46063 | 2/20 | 0.79 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.79 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.79 |
| ▸ | F3 | P13726 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL2128854 | 1.00 | CYP1A2 (0.79) | CYP1A2CYP2C9MAPTPLIN1LMNA | |
| Chloroform SCHEMBL1827856 | 1.00 | CYP1A2 (0.79) | CYP1A2CYP2C9MAPTPLIN1LMNA | |
| Chloroform SCHEMBL7629150 | 1.00 | CYP1A2 (0.79) | CYP1A2CYP2C9MAPTPLIN1LMNA | |
| Chloroform SCHEMBL2128849 | 1.00 | CYP1A2 (0.79) | CYP1A2CYP2C9MAPTPLIN1LMNA | |
| Chloroform SCHEMBL84057 | 1.00 | CYP1A2 (0.79) | CYP1A2CYP2C9MAPTPLIN1LMNA | |
| Chloroform SCHEMBL2832028 | 1.00 | CYP1A2 (0.79) | CYP1A2CYP2C9MAPTPLIN1LMNA | |
| Chloroform SCHEMBL18788602 | 1.00 | CYP1A2 (0.79) | CYP1A2CYP2C9MAPTPLIN1LMNA | |
| Chloroform SCHEMBL28370740 | 1.00 | CYP1A2 (0.79) | CYP1A2CYP2C9MAPTPLIN1LMNA | |
| Chloroform SCHEMBL29371090 | 1.00 | CYP1A2 (0.79) | CYP1A2CYP2C9MAPTPLIN1LMNA | |
| Chloroform SCHEMBL1043119 | 0.98 | CYP1A2 (0.83) | CYP1A2CYP2C9MAPTPLIN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000486-B2 | Antiviral drugs for treatment of arenavirus infection | KINETA VIRAL HEMORRHAGIC FEVER, LLC (US) | 2018-06-19 | — | — | US | disclosed |
| EP-2814486-B1 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | KINETA FOUR LLC (US) | 2018-04-11 | — | — | EP | disclosed |
| US-20170137422-A1 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | Kineta Four, LLC (US) | 2017-05-18 | — | — | US | disclosed |
| US-9498470-B2 | Antiviral drugs for treatment of arenavirus infection | Kineta Four, LLC (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150023916-A1 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | SIGA TECHNOLOGIES INC. (US) | 2015-01-22 | — | — | US | disclosed |
| US-8673891-B2 | Aminopyrazine derivative and medicine | NIPPON SHINYAKU CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| EP-2394999-B1 | AMINOPYRAZINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2014-01-29 | — | — | EP | disclosed |
| US-8586591-B2 | Aminopyrazine derivative and medicine | NIPPON SHINYAKU CO., LTD. (JP) | 2013-11-19 | — | — | US | disclosed |
| EP-2394999-A1 | AMINOPYRAZINE DERIVATIVE AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110288065-A1 | AMINOPYRAZINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-6982257-B1 | Vitamin D3 derivative and its production method | TEIJIN LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| EP-0957088-B1 | VITAMIN D3 DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | TEIJIN LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| EP-0957088-A1 | VITAMIN D3 DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1999-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000486-B2 | Antiviral drugs for treatment of arenavirus infection | EIF2AK2, ZC3HAV1, SARS1 | CYP1A2 4179/4885CYP2C9 3296/4885MAPT 4118/4885 |
| US-20150023916-A1 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | EIF2AK2, ZC3HAV1, SARS1 | CYP1A2 4179/4885CYP2C9 3296/4885MAPT 4118/4885 |
| US-20170137422-A1 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | EIF2AK2, ZC3HAV1, SARS1 | CYP1A2 4179/4885CYP2C9 3296/4885MAPT 4118/4885 |
| US-20110288065-A1 | AMINOPYRAZINE DERIVATIVE AND MEDICINE | MC2R, CNR1, NPY2R | CYP1A2 136/4885CYP2C9 397/4885MAPT 4014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.