Chloroform

Chloroform

SCHEMBL84057

ClC(Cl)Cl.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.79
CYP2C9 P11712 3/20 0.79
MAPT P10636 3/20 0.79
PLIN1 O60240 2/20 0.79
LMNA P02545 2/20 0.79
RECQL P46063 2/20 0.79
PLIN5 Q00G26 2/20 0.79
ABHD5 Q8WTS1 2/20 0.79
CYP2D6 P10635 2/20 0.79
F3 P13726 2/20 0.79
ALDH1A1 P00352 2/20 0.79
SMN1; SMN2 Q16637 1/20 0.79
HDAC3 O15379 2/20 0.59
HDAC4 P56524 2/20 0.59
HDAC1 Q13547 2/20 0.59
HDAC2 Q92769 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59
TNKS O95271 1/20 0.59
HCAR2 Q8TDS4 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL1367016 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL2128854 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL1827856 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL7629150 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL2128849 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL2832028 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL18788602 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL28370740 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL29371090 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL1043119 0.98 CYP1A2 (0.83) CYP1A2CYP2C9MAPTPLIN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 838 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040462-A Spiropyrazinone compound, preparation method and application 北京工业大学 2025-05-27 CN claimed
CN-120040461-A Spirobarbitudes compound, preparation method and application 北京工业大学 2025-05-27 CN claimed
CN-119569557-A Method for synthesizing linear carboxylic acid by olefin hydrocarboxylation with formic acid as carbonyl source 常州大学 2025-03-07 CN claimed
CN-118406075-A Silicon-containing polycyclic chromone skeleton compound, preparation method and application thereof 遵义医科大学 2024-07-30 CN claimed
CN-118344383-A 11-Membered ring compound containing Z-type double bond and preparation method thereof 天津大学 2024-07-16 CN claimed
CN-118344303-A Benzo [ c ] [1,5] oxazacine compound and synthesis method thereof 江苏师范大学 2024-07-16 CN claimed
CN-118324794-A Nitrogen-containing silicon cyclohexene compound and preparation method thereof 扬州大学 2024-07-12 CN claimed
CN-118307475-A Preparation method of stable isotope labeled fluxapyroxad internal standard reagent 谱同生物医药科技(常州)有限公司 2024-07-09 CN claimed
CN-118307554-A E-containing double bond 11-membered ring compound and preparation method thereof 天津大学 2024-07-09 CN claimed
CN-118290432-A Trans-cycloolefin compound and preparation method and application thereof 华中师范大学 2024-07-05 CN claimed
CN-108440526-A A kind of chirality barbital spiral shell Tetrahydroquinolinesas and preparation method 北京工业大学 2018-08-24 CN claimed
US-8487109-B2 Process for the palladium-catalyzed coupling of terminal alkynes with aryl tosylates SANOFI (FR) 2013-07-16 US claimed
US-20100261910-A1 Process for the palladium-catalyzed coupling of terminal alkynes with aryl tosylates SANOFI-AVENTIS (FR) 2010-10-14 US claimed
EP-1648858-B1 METHOD FOR PRODUCTION OF ALPHA, BETA-UNSATURATED AMIDE COMPOUNDS SIEGFRIED GENERICS INT AG (CH) 2008-07-02 EP claimed
US-20060281949-A1 Method for production $g(a),$g(b)-unsaturated amide compounds SIEGFRIED GENERICS INTERNATIONAL AG (CH) 2006-12-14 US claimed
EP-1068209-B1 PROCESS FOR THE PRODUCTION OF PURINE DERIVATIVES AND INTERMEDIATES THEREFOR NOVARTIS INT PHARM LTD (BM) 2005-09-14 EP claimed
US-20050049278-A1 Benzo[1,3]dioxole compounds, pharmaceutical compositions thereof, and processes of making and using the same ATHERSYS, INC. 2005-03-03 US claimed
US-20030130512-A1 Process for the production of purine derivatives and intermediates therefor DPT LABORATORIES, LTD. 2003-07-10 US claimed
US-6555685-B1 Preparing purine derivatives, such as famiciclovir and penciclovir, by reacting, in the presence of a palladium catalyst and ligand; by-product inhibition; efficiency NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) 2003-04-29 US claimed
EP-0444889-A1 Novel synthesis of carbapenem intermediates MERCK & CO. INC. (US) 1991-09-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130512-A1 Process for the production of purine derivatives and intermediates therefor TYMP, DPYD, PNP CYP1A2 1949/4885CYP2C9 763/4885MAPT 3521/4885
US-20060281949-A1 Method for production $g(a),$g(b)-unsaturated amide compounds GSTA2, GSTO1, GLB1 CYP1A2 288/4885CYP2C9 491/4885MAPT 3147/4885
US-20100261910-A1 Process for the palladium-catalyzed coupling of terminal alkynes with aryl tosylates TYR, ALK, TYRO3 CYP1A2 155/4885CYP2C9 479/4885MAPT 4717/4885
US-20050049278-A1 Benzo[1,3]dioxole compounds, pharmaceutical compositions thereof, and processes of making and using the same CYP4X1, BBOX1, CYP1B1 CYP1A2 30/4885CYP2C9 16/4885MAPT 2581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.