Chloroform

Chloroform

SCHEMBL1827856

ClC(Cl)Cl.O=C(/C=C\c1ccccc1)/C=C/c1ccccc1.O=C(/C=C\c1ccccc1)/C=C/c1ccccc1.O=C(/C=C\c1ccccc1)/C=C/c1ccccc1.[Pd].[Pd]

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.79
CYP2C9 P11712 3/20 0.79
MAPT P10636 3/20 0.79
PLIN1 O60240 2/20 0.79
LMNA P02545 2/20 0.79
RECQL P46063 2/20 0.79
PLIN5 Q00G26 2/20 0.79
ABHD5 Q8WTS1 2/20 0.79
CYP2D6 P10635 2/20 0.79
F3 P13726 2/20 0.79
ALDH1A1 P00352 2/20 0.79
SMN1; SMN2 Q16637 1/20 0.79
HDAC3 O15379 2/20 0.59
HDAC4 P56524 2/20 0.59
HDAC1 Q13547 2/20 0.59
HDAC2 Q92769 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59
TNKS O95271 1/20 0.59
HCAR2 Q8TDS4 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL1367016 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL2128854 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL7629150 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL2128849 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL84057 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL2832028 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL18788602 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL28370740 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL29371090 1.00 CYP1A2 (0.79) CYP1A2CYP2C9MAPTPLIN1LMNA
Chloroform SCHEMBL1043119 0.98 CYP1A2 (0.83) CYP1A2CYP2C9MAPTPLIN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021212974-A1 RACEMIC AND CHIRAL 3-(2,3-BUTADIENYL)OXYINDOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 复旦大学 (CN) 2021-10-28 WO claimed
CN-109369667-A 2,3,6- tri- deoxidation glycosyl demethylated podophyllotoxin compounds and its preparation method and application 南通大学 2019-02-22 CN claimed
CN-105732495-B Tetrahydroquinolinesas with optical activation and preparation method thereof 华中师范大学 2018-11-09 CN claimed
CN-105732550-B A method of preparing chiral 3- methylene -2,3-dihydrofuran class compound DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2018-08-31 CN claimed
EP-3455224-B1 SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF BAYER AG (DE) 2024-03-27 EP disclosed
WO-2023189861-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT, METHOD FOR PRODUCING SAME, DISPLAY DEVICE, AND LIGHTING DEVICE 三菱ケミカル株式会社 2023-10-05 WO disclosed
EP-3269789-B1 LIGHT EMITTING MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-08-30 EP disclosed
WO-2022268119-A1 SULFOXIMINE COMPOUND AND USE THEREOF 南京明德新药研发有限公司 2022-12-29 WO disclosed
US-10559761-B2 Light-emitting material, and organic electroluminescent device KYULUX, INC. (JP) 2020-02-11 US disclosed
CN-106415398-B Electrophtography photosensor, electrographic cartridge, image forming apparatus and charge transport materials 三菱化学株式会社 2019-11-19 CN disclosed
CN-106483779-B Laminated electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2019-10-18 CN disclosed
CN-106854191-B 2- 3- methylene -2,3-dihydrofuran synthetic methods containing chiral quaternary carbon center 中国科学院大连化学物理研究所 2019-09-27 CN disclosed
EP-0854138-B1 Vitamin D3 derivative and production process thereof TEIJIN LTD (JP) 2001-05-23 EP disclosed
US-6177586-B1 USEFUL AS A PHARMACEUTICAL SUCH AS AN AGENT FOR PROMOTING BONE FORMATION, AN AGENT FOR SUPPRESSING PROLIFERATION OF TUMOR CELLS, AN AGENT FOR HIGH CALCIUM BLOOD DISEASES, AND AN IMMUNOSUPPRESSION AGENT TEIJIN LIMITED (JP) 2001-01-23 US disclosed
EP-0712843-B1 VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5986112-A STEROID DERIVATIVES AS ANTITUMOR AGENTS AND BLOOD METAL CONCENTRATES TEIJIN LIMITED (JP) 1999-11-16 US disclosed
EP-0854139-A2 Vitamin D3 derivative and production process thereof TEIJIN LIMITED (JP) 1998-07-22 EP disclosed
EP-0854138-A2 Vitamin D3 derivative and production process thereof TEIJIN LIMITED (JP) 1998-07-22 EP disclosed
US-5719297-A Vitamin D3 derivatives and production process thereof TEIJIN LIMITED (JP) 1998-02-17 US disclosed
EP-0712843-A1 VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1996-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10559761-B2 Light-emitting material, and organic electroluminescent device EML4, L1CAM, CRY1 CYP1A2 477/4885CYP2C9 166/4885MAPT 1622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.