SCHEMBL13670909

SCHEMBL13670909

CC(C)(C)OC(=O)NC(Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PCNA P12004 11/20 0.58
CTSS P25774 1/20 0.51
CTSK P43235 1/20 0.51
ACE P12821 1/20 0.51
ITGB3 P05106 1/20 0.51
ITGA2B P08514 1/20 0.51
PTPN1 P18031 2/20 0.49
LIG1 P18858 1/20 0.49
SCN9A Q15858 1/20 0.46
THRB P10828 2/20 0.46
LMNA P02545 1/20 0.46
CYP2D6 P10635 1/20 0.46
THRA P10827 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5177568 1.00 PCNA (0.58) PCNACTSSCTSKACEITGB3
SCHEMBL5177663 1.00 PCNA (0.58) PCNACTSSCTSKACEITGB3
SCHEMBL8205060 0.90 THRB (0.60) PCNAACEITGB3ITGA2BTHRB
SCHEMBL5177146 0.90 THRB (0.60) PCNAACEITGB3ITGA2BTHRB
SCHEMBL5177770 0.90 THRB (0.60) PCNAACEITGB3ITGA2BTHRB
SCHEMBL10780803 0.89 THRB (0.59) PCNACTSSCTSKACEITGB3
SCHEMBL8417806 0.89 THRB (0.59) PCNACTSSCTSKACEITGB3
SCHEMBL1526069 0.89 THRB (0.59) PCNACTSSCTSKACEITGB3
SCHEMBL13952218 0.87 ACE (0.50) PCNACTSSCTSKACEITGB3
Ethylenediamine SCHEMBL11090366 0.85 THRB (0.57) PCNAACEITGB3ITGA2BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240057599-A1 METHODS FOR IMPROVING FRUIT QUALITY THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2024-02-22 US disclosed
US-11812746-B2 Method of controlling fungal infections in plants THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2023-11-14 US disclosed
US-20200383327-A1 METHOD OF IMPROVING PLANT PERFORMANCE THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2020-12-10 US disclosed
US-20190246639-A1 METHOD OF CONTROLLING FUNGAL INFECTIONS IN PLANTS THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCHORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2019-08-15 US disclosed
US-7608465-B2 Multi-analyte diagnostic test for thyroid disorders BIO-RAD LABORATORIES, INC. (US) 2009-10-27 US disclosed
US-7608465-B2 Multi-analyte diagnostic test for thyroid disorders BIO-RAD LABORATORIES, INC. (US) 2009-10-27 US disclosed
US-7271009-B1 Multi-analyte diagnostic test for thyroid disorders BIO-RAD LABORATORIES, INC. (US) 2007-09-18 US disclosed
US-20070178604-A1 Multi-analyte diagnostic test for thyroid disorders BIO-RAD LABORATORIES, INC. (US) 2007-08-02 US disclosed
US-20070178604-A1 Multi-analyte diagnostic test for thyroid disorders BIO-RAD LABORATORIES, INC. (US) 2007-08-02 US disclosed