Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455094 | 0.81 | ALDH1A1 (0.59) | NPSR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL13672523 | 0.80 | ALDH1A1 (0.39) | NPSR1LMNAMEN1KMT2AMAPT | |
| SCHEMBL13672184 | 0.80 | ALDH1A1 (0.46) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL13672414 | 0.80 | ALDH1A1 (0.42) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13672183 | 0.79 | ALDH1A1 (0.41) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL13672416 | 0.78 | ALDH1A1 (0.45) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13672178 | 0.78 | ALDH1A1 (0.42) | LMNAMEN1KMT2ATSHRMAPT | |
| SCHEMBL13672173 | 0.78 | PREP (0.45) | MEN1KMT2ATSHRALDH1A1HTT | |
| SCHEMBL13672415 | 0.78 | CYP3A4 (0.44) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13672177 | 0.78 | DPP4 (0.41) | LMNAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264414-A1 | Amide Derivatives and Pharmaceutical Use Thereof | HIGH POINT PHARMACEUTICALS, LLC (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264414-A1 | Amide Derivatives and Pharmaceutical Use Thereof | HSD11B1, HSD11B2, HSD3B1 | NPSR1 1604/4885LMNA 3531/4885MEN1 2564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.