Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.97 |
| ▸ | MEN1 | O00255 | 8/20 | 0.97 |
| ▸ | HTT | P42858 | 7/20 | 0.97 |
| ▸ | LMNA | P02545 | 4/20 | 0.97 |
| ▸ | THRB | P10828 | 3/20 | 0.97 |
| ▸ | MMP14 | P50281 | 1/20 | 0.97 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.70 |
| ▸ | INSR | P06213 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26845318 | 0.85 | MAPT (0.72) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL11289314 | 0.82 | ADRB2 (1.00) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL30924935 | 0.82 | ADRB2 (1.00) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL5020834 | 0.82 | ADRB2 (1.00) | MAPTKMT2AMEN1HTTLMNA | |
| Perchlorate SCHEMBL11444833 | 0.81 | KMT2A (0.66) | MAPTKMT2AMEN1HTTLMNA | |
| Perchlorate SCHEMBL11444832 | 0.81 | KMT2A (0.66) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL17322556 | 0.80 | INSR (0.75) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL16800102 | 0.79 | MAPT (0.63) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL12439978 | 0.77 | MAPT (0.61) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL10603061 | 0.77 | MEN1 (0.61) | MAPTKMT2AMEN1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598385-B2 | Asymmetric cyanine fluorescent dyes | SHENZHEN MINDRAY BIOMEDICAL ELECTRONICS CO., LTD. (CN) | 2009-10-06 | — | — | US | disclosed |
| US-20090017441-A1 | Reacting unsubstituted or substituted 2-methylbenzothiazole, 2-methylbenzooxazole or 2,3,3-trimethyl-3H-indoline with substituted or unsubstituted benzylhalide, forming 4-methylquinoline quaternary ammonium salt intermediates, condensing with N,N'-diphenylformamidine; for staining nucleic acids | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017441-A1 | Reacting unsubstituted or substituted 2-methylbenzothiazole, 2-methylbenzooxazole or 2,3,3-trimethyl-3H-indoline with substituted or unsubstituted benzylhalide, forming 4-methylquinoline quaternary ammonium salt intermediates, condensing with N,N'-diphenylformamidine; for staining nucleic acids | RCC1, DNMT3A, H1-4 | MAPT 2247/4885KMT2A 187/4885MEN1 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.