Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424929 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL4428390 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL6475271 | 0.78 | SHMT1 (0.48) | SMN1; SMN2ALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL6481421 | 0.78 | THRB (0.46) | SMN1; SMN2ALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL6475294 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPK1LMNATHRB | |
| SCHEMBL6475063 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL4435090 | 0.75 | LPAR1 (0.41) | SMN1; SMN2ALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL4433288 | 0.75 | TAS1R3 (0.42) | SMN1; SMN2ALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL6473687 | 0.74 | LPAR1 (0.42) | SMN1; SMN2ALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL6344303 | 0.73 | ALDH1A1 (0.55) | ALDH1A1MAPK1HPGDLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741700-B1 | 1-H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES AS PEST-CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2009-10-07 | — | — | EP | disclosed |