Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377889 | 0.95 | TSHR (0.50) | TSHRALDH1A1CNR2AOC3CTSK | |
| SCHEMBL9283313 | 0.90 | CNR2 (0.52) | TSHRALDH1A1CNR2KDM4ERIPK1 | |
| SCHEMBL13900455 | 0.86 | OPRK1 (0.51) | TSHRALDH1A1AOC3SLC6A2TAAR1 | |
| SCHEMBL9281438 | 0.86 | HRH3 (0.50) | TSHRALDH1A1CNR2CTSKKDM4E | |
| SCHEMBL13900464 | 0.85 | MEN1 (0.53) | TSHRALDH1A1CNR2KDM4EMAPK1 | |
| SCHEMBL25062252 | 0.83 | MAPT (0.50) | CNR2SLC6A2MEN1KMT2ASLC6A4 | |
| SCHEMBL9284639 | 0.82 | OPRM1 (0.46) | TSHRALDH1A1CNR2KDM4EOPRK1 | |
| SCHEMBL9281673 | 0.80 | ALDH1A1 (0.54) | TSHRALDH1A1AOC3KDM4ERIPK1 | |
| SCHEMBL2518042 | 0.78 | ALDH1A1 (0.46) | TSHRALDH1A1CNR2AOC3KDM4E | |
| SCHEMBL10506662 | 0.78 | SLC6A2 (0.54) | TSHRALDH1A1CNR2AOC3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608619-B2 | Substituted oxazole compounds with analgesic activity | GRUENENTHAL GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| US-7608619-B2 | Substituted oxazole compounds with analgesic activity | GRUENENTHAL GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| US-20090069330-A1 | Substituted Oxazole Compounds with Analgesic Activity | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090069330-A1 | Substituted Oxazole Compounds with Analgesic Activity | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069330-A1 | Substituted Oxazole Compounds with Analgesic Activity | OPRK1, OPRD1, OPRM1 | TSHR 4202/4885ALDH1A1 6/4885CNR2 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.