Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 19/20 | 0.42 |
| ▸ | F13A1 | P00488 | 2/20 | 0.40 |
| ▸ | TGM1 | P22735 | 2/20 | 0.40 |
| ▸ | TGM6 | O95932 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711557 | 0.90 | TGM2 (0.45) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL13674472 | 0.89 | TGM2 (0.46) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL13674665 | 0.76 | TGM2 (0.43) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL13674663 | 0.76 | TGM2 (0.43) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL14445101 | 0.75 | TGM2 (0.41) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL13671325 | 0.75 | MEN1 (0.50) | TGM2 | |
| SCHEMBL12737512 | 0.74 | ACHE (0.49) | ACHETGM2 | |
| SCHEMBL16072730 | 0.73 | ITGB3 (0.42) | TGM2F13A1TGM1 | |
| SCHEMBL12737514 | 0.73 | ACHE (0.50) | ACHE | |
| SCHEMBL13498637 | 0.72 | ITGB3 (0.42) | TGM2F13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605166-B2 | Synergistic mixture of methotrexate and integrin antigen or antibody | ELAN PHARMACEUTICALS INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7595318-B2 | Polyethylene glycol conjugates of heterocycloalkyl carboxamido propanoic acids | ELAN PHARMACEUTICALS, INC. (US) | 2009-09-29 | — | — | US | disclosed |