Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 18/20 | 0.41 |
| ▸ | F13A1 | P00488 | 2/20 | 0.40 |
| ▸ | TGM1 | P22735 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | TGM6 | O95932 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711557 | 0.85 | TGM2 (0.45) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL16181039 | 0.82 | TGM2 (0.48) | TGM2 | |
| SCHEMBL13674663 | 0.81 | TGM2 (0.43) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL13671325 | 0.80 | MEN1 (0.50) | TGM2 | |
| SCHEMBL13498637 | 0.79 | ITGB3 (0.42) | TGM2F13A1TGM1 | |
| SCHEMBL16072730 | 0.78 | ITGB3 (0.42) | TGM2F13A1TGM1 | |
| SCHEMBL13674472 | 0.77 | TGM2 (0.46) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL13674476 | 0.75 | ACHE (0.43) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL327848 | 0.75 | EPHX1 (0.38) | TGM2 | |
| SCHEMBL10017795 | 0.75 | EPHX1 (0.38) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070166277-A1 | Polymeric reagents comprising a ketone or a related functional group | NEKTAR THERAPEUTICS | 2007-07-19 | — | — | US | disclosed |
| US-7208145-B2 | Useful for providing conjugates with other substances | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2007-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166277-A1 | Polymeric reagents comprising a ketone or a related functional group | TKT, KHK, KLK5 | TGM2 1364/4885F13A1 1406/4885TGM1 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.