Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673204 | 0.86 | KDM4E (0.42) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL13675162 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL13675157 | 0.79 | CNR2 (0.40) | ALDH1A1KDM4EGAAMAPTMAPK1 | |
| SCHEMBL18963419 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL7150414 | 0.72 | EGFR (0.47) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL7249167 | 0.71 | EGFR (0.43) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL6984098 | 0.71 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL29335488 | 0.70 | CNR2 (0.46) | ALDH1A1KDM4EMAPTMAPK1CNR2 | |
| SCHEMBL22340909 | 0.70 | CETP (0.46) | MAPTCNR2LMNACNR1 | |
| SCHEMBL16219153 | 0.70 | SLC6A2 (0.38) | ALDH1A1KDM4EGAAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608619-B2 | Substituted oxazole compounds with analgesic activity | GRUENENTHAL GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| US-20090069330-A1 | Substituted Oxazole Compounds with Analgesic Activity | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069330-A1 | Substituted Oxazole Compounds with Analgesic Activity | OPRK1, OPRD1, OPRM1 | ALDH1A1 6/4885KDM4E 2740/4885GAA 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.