Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346685 | 0.89 | RAB9A (0.53) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL31346686 | 0.89 | S1PR1 (0.57) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL31346675 | 0.84 | RAB9A (0.49) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL31346703 | 0.84 | RAB9A (0.49) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL12866 | 0.84 | RAB9A (0.69) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL14873253 | 0.84 | L3MBTL1 (0.53) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL10066488 | 0.84 | L3MBTL1 (0.72) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL22562768 | 0.83 | NOTUM (0.57) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL24092055 | 0.83 | TP53 (0.52) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL14873337 | 0.83 | L3MBTL1 (0.51) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | CORBETT JEFFREY WAYNE | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | ACACA, PC, ACACB | RAB9A 1738/4885NPC1 715/4885L3MBTL1 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.