Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ATF4 | P18848 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13674552 | 0.90 | ACVRL1 (0.36) | FFAR4HSD11B1HPGDOPRM1OPRD1 | |
| SCHEMBL13674511 | 0.89 | HSD11B1 (0.47) | HSD11B1HPGDKDM4EMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4522836 | 0.89 | ACVRL1 (0.36) | FFAR4HSD11B1HPGDOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL4514348 | 0.88 | HSD11B1 (0.46) | HSD11B1HPGDKDM4EMAOAMAOB | |
| SCHEMBL13675466 | 0.82 | NPC1 (0.41) | FFAR4HPGD | |
| SCHEMBL13675471 | 0.82 | SLC6A9 (0.42) | FFAR4HSD11B1HTR1AALDH1A1 | |
| SCHEMBL13675463 | 0.82 | HSD11B1 (0.37) | FFAR4HSD11B1OPRM1OPRD1OPRK1 | |
| SCHEMBL4514955 | 0.81 | S1PR1 (0.40) | FFAR4HSD11B1HPGDOPRM1OPRD1 | |
| SCHEMBL13675515 | 0.81 | MAPT (0.41) | FFAR4HSD11B1 | |
| SCHEMBL4525800 | 0.79 | HSD11B1 (0.47) | HSD11B1HPGDKDM4EFFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | FFAR4 1012/4885HSD11B1 1/4885HPGD 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.