Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952636 | 0.89 | DPP4 (0.36) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL16549063 | 0.89 | LMNA (0.35) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL24851125 | 0.89 | DPP4 (0.36) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL23059125 | 0.87 | DPP4 (0.39) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL20146595 | 0.85 | TSHR (0.40) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL17169612 | 0.85 | TSHR (0.40) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL19449636 | 0.85 | TSHR (0.40) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL24613029 | 0.83 | DPP4 (0.32) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL20408261 | 0.83 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL24063407 | 0.83 | TSHR (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11801528-B2 | Carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2023-10-31 | — | — | US | disclosed |
| WO-2023135582-A1 | NEW STEREORETENTIVE RUTHENIUM COMPLEXES, METHOD OF THEIR PREPARATION, INTERMEDIATES USED IN THIS METHOD AND USE OF NEW STEREORETENTIVE RUTHENIUM COMPLEXES IN OLEFIN METATHESIS REACTIONS | UNIWERSYTET WARSZAWSKI (PL) | 2023-07-20 | — | — | WO | disclosed |
| US-20220009854-A1 | A SERIES OF CATALYSTS FOR THE HYPERPOLARISATION OF SUBSTRATES | UNIVERSITY OF YORK (GB) | 2022-01-13 | — | — | US | disclosed |
| EP-3720885-B1 | METHOD FOR PRODUCING NITRILE RUBBERS WITH RUTHENIUM COMPLEX CATALYSTS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2021-12-01 | — | — | EP | disclosed |
| US-9932359-B2 | Organic electroluminescent materials and devices | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-04-03 | — | — | US | disclosed |
| US-9773986-B2 | Copper(I)-carbene complexes and organic electroluminescent devices | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-09-26 | — | — | US | disclosed |
| EP-2501707-B1 | 3-COORDINATE COPPER (I) - CARBENE COMPLEXES | UNIV SOUTHERN CALIFORNIA (US) | 2017-08-02 | — | — | EP | disclosed |
| US-20170018599-A1 | Pyridone Dye Composition | CLARIANT INTERNATIONAL LTD. (CH) | 2017-01-19 | — | — | US | disclosed |
| US-9464097-B2 | Gold complexes | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2016-10-11 | — | — | US | disclosed |
| US-20160199875-A1 | Carbene-Functionalized Composite Materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2016-07-14 | — | — | US | disclosed |
| US-20160199875-A1 | Carbene-Functionalized Composite Materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2016-07-14 | — | — | US | disclosed |
| US-20160016976-A2 | GOLD COMPLEXES | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2016-01-21 | — | — | US | disclosed |
| WO-2011154700-A1 | CARBOXYLATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2011-12-15 | — | — | WO | disclosed |
| US-20090264417-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | KALYPSYS, INC. (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009854-A1 | A SERIES OF CATALYSTS FOR THE HYPERPOLARISATION OF SUBSTRATES | SPR, YAP1, KRAS | GABRA1 4805/4885GABRG2 4154/4885GABRB3 4376/4885 |
| US-20160016976-A2 | GOLD COMPLEXES | MCL1, HUNK, DKC1 | GABRA1 2739/4885GABRG2 2487/4885GABRB3 2030/4885 |
| US-20090264417-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | PPARG, PPARA, PPARD | GABRA1 251/4885GABRG2 249/4885GABRB3 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.