Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675514 | 0.91 | RORC (0.38) | SMN1; SMN2HPGDLMNAMAPTALDH1A1 | |
| SCHEMBL4514917 | 0.84 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2HPGDLMNA | |
| SCHEMBL4502644 | 0.77 | EPHX2 (0.42) | SMN1; SMN2HPGDEPHX2 | |
| SCHEMBL4508795 | 0.76 | NPY2R (0.35) | MEN1KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL4513595 | 0.75 | HSD11B1 (0.46) | SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL4511944 | 0.75 | HSD11B1 (0.52) | MEN1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL5548898 | 0.75 | RORC (0.39) | SMN1; SMN2HPGDMAPTALDH1A1 | |
| SCHEMBL4516607 | 0.75 | HSD11B1 (0.44) | MEN1KMT2ASMN1; SMN2HPGDHTT | |
| SCHEMBL4505773 | 0.74 | NPC1 (0.53) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL4505594 | 0.74 | HSD11B1 (0.53) | MEN1KMT2ASMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | MEN1 1254/4885KMT2A 2379/4885SMN1; SMN2 4487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.