Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4510127 | 0.89 | HSD11B1 (0.47) | HSD11B1HPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13674559 | 0.88 | HSD11B1 (0.43) | HSD11B1HPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4505773 | 0.87 | NPC1 (0.53) | HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4514812 | 0.87 | ALDH1A1 (0.46) | HSD11B1HPGDALDH1A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL4515008 | 0.87 | HSD11B1 (0.42) | HSD11B1HPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4508949 | 0.86 | HSD11B1 (0.43) | HSD11B1HPGDALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL4501753 | 0.85 | HSD11B1 (0.48) | HSD11B1HPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4516607 | 0.85 | HSD11B1 (0.44) | HSD11B1HPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4511944 | 0.85 | HSD11B1 (0.52) | HSD11B1HPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5543818 | 0.85 | HSD11B1 (0.43) | HSD11B1HPGDALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | HSD11B1 1/4885HPGD 63/4885ALDH1A1 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.