Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLI1 | P08151 | 2/20 | 0.68 |
| ▸ | GLI2 | P10070 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533548 | 0.86 | GLI1 (0.81) | GLI1GLI2PTGS1PTGS2TRPV1 | |
| SCHEMBL27598564 | 0.84 | PTGS1 (0.65) | GLI1GLI2PTGS1PTGS2TRPV1 | |
| SCHEMBL1891876 | 0.84 | PTGS1 (0.65) | GLI1GLI2PTGS1PTGS2TRPV1 | |
| SCHEMBL12608944 | 0.84 | GLI1 (0.64) | GLI1GLI2PTGS1PTGS2TRPV1 | |
| SCHEMBL11533724 | 0.81 | PTGS1 (0.60) | GLI1GLI2PTGS1PTGS2TRPV1 | |
| SCHEMBL9878055 | 0.81 | PTGS1 (0.72) | GLI1GLI2PTGS1PTGS2TRPV1 | |
| SCHEMBL11531868 | 0.81 | PTGS1 (0.72) | GLI1GLI2PTGS1PTGS2TRPV1 | |
| SCHEMBL27550082 | 0.81 | PTGS1 (0.56) | GLI1GLI2PTGS1PTGS2TRPV1 | |
| SCHEMBL6329742 | 0.81 | PTGS1 (0.56) | GLI1GLI2PTGS1PTGS2TRPV1 | |
| SCHEMBL11533087 | 0.80 | GLI1 (0.59) | GLI1GLI2PTGS1PTGS2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO., LTD. (CN) | 2009-09-24 | — | — | US | disclosed |
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO., LTD. (CN) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | GLI1 3844/4885GLI2 3275/4885PTGS1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.