Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380433 | 0.83 | LMNA (0.31) | L3MBTL1NPSR1LMNAMAPTTDP1 | |
| SCHEMBL296284 | 0.78 | MAPT (0.46) | L3MBTL1NPSR1MGLLMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL34870 | 0.76 | MAPT (0.44) | L3MBTL1NPSR1MGLLMEN1KMT2A | |
| SCHEMBL18596315 | 0.76 | MAPT (0.46) | L3MBTL1HPGDMGLLHRH3NOTUM | |
| SCHEMBL5352313 | 0.73 | MAPT (0.42) | L3MBTL1HPGDNPSR1NOTUMMEN1 | |
| SCHEMBL20251137 | 0.70 | MAPT (0.51) | L3MBTL1HPGDMGLLHRH3MEN1 | |
| SCHEMBL4792425 | 0.69 | MGLL (0.47) | L3MBTL1HPGDNPSR1MGLLHRH3 | |
| SCHEMBL13969813 | 0.68 | NOTUM (0.50) | L3MBTL1HPGDNPSR1MGLLNOTUM | |
| SCHEMBL16786535 | 0.67 | MGLL (0.45) | L3MBTL1HPGDNPSR1MGLLNOTUM | |
| SCHEMBL277165 | 0.67 | ALDH1A1 (0.54) | L3MBTL1HPGDNPSR1MGLLHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582770-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-01 | — | — | US | disclosed |