Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153658 | 0.90 | HSD17B10 (0.65) | PNPLA2HDAC6TP53HSD17B10MEN1 | |
| SCHEMBL13680447 | 0.89 | PNPLA2 (0.62) | PNPLA2HDAC6CNR1KMT2A | |
| SCHEMBL13681314 | 0.83 | CNR1 (0.65) | CNR1TP53HSD17B10MEN1KMT2A | |
| SCHEMBL19019393 | 0.82 | TP53 (0.69) | PNPLA2HDAC6TP53APEX1 | |
| SCHEMBL13680541 | 0.81 | HSD17B10 (0.79) | CNR1HSD17B10MEN1KMT2AKCNK3 | |
| SCHEMBL15186954 | 0.81 | PNPLA2 (1.00) | PNPLA2HDAC6TP53MEN1KMT2A | |
| SCHEMBL13680547 | 0.80 | CNR1 (0.61) | CNR1HSD17B10MEN1KMT2AKCNK3 | |
| SCHEMBL13680515 | 0.79 | FAAH (0.66) | CNR1TP53HSD17B10MEN1KMT2A | |
| SCHEMBL13680542 | 0.79 | CNR1 (0.68) | CNR1HSD17B10MEN1KMT2AKCNK3 | |
| SCHEMBL7618599 | 0.78 | HSD17B10 (0.62) | HSD17B10MEN1KMT2AHSP90AA1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |