Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | NQO2 | P16083 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742509 | 0.91 | HSD17B10 (0.66) | HSD17B10CNR1NQO2RAB9ANPC1 | |
| SCHEMBL12133 | 0.89 | HSD17B10 (1.00) | HSD17B10RAB9ARXFP1ALDH1A1CYP1A2 | |
| SCHEMBL30703669 | 0.89 | HSD17B10 (1.00) | HSD17B10RAB9ARXFP1ALDH1A1CYP1A2 | |
| SCHEMBL8265472 | 0.88 | HSD17B10 (0.66) | HSD17B10CNR1RAB9ANPC1RXFP1 | |
| SCHEMBL12999591 | 0.88 | NPC1 (0.69) | HSD17B10NQO2RAB9ANPC1RXFP1 | |
| SCHEMBL13681314 | 0.87 | CNR1 (0.65) | HSD17B10CNR1RXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3786463 | 0.85 | NQO2 (0.73) | HSD17B10CNR1NQO2RAB9ANPC1 | |
| SCHEMBL13680547 | 0.84 | CNR1 (0.61) | HSD17B10CNR1RXFP1CYP1A2MGLL | |
| SCHEMBL8577619 | 0.84 | SMN1; SMN2 (0.70) | HSD17B10CNR1NQO2RAB9ANPC1 | |
| SCHEMBL13680515 | 0.83 | FAAH (0.66) | HSD17B10CNR1RAB9ANPC1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |