Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680535 | 0.89 | PNPLA2 (0.68) | PNPLA2HDAC6CNR1KMT2A | |
| SCHEMBL8265472 | 0.82 | HSD17B10 (0.66) | AOC3HSD17B1HSD17B2CNR1CSF1R | |
| SCHEMBL8153658 | 0.82 | HSD17B10 (0.65) | PNPLA2HDAC6KMT2A | |
| SCHEMBL13680497 | 0.81 | KIF11 (0.69) | HSD17B1HSD17B2CNR1CSF1RFLT1 | |
| SCHEMBL13680466 | 0.79 | FAAH (0.56) | HSD17B1HSD17B2CNR1CSF1RFLT1 | |
| SCHEMBL13680444 | 0.79 | CNR1 (0.62) | HSD17B1HSD17B2CNR1CSF1RFLT1 | |
| SCHEMBL4770587 | 0.77 | TSHR (0.68) | TSHR | |
| SCHEMBL687878 | 0.77 | TSHR (0.79) | TSHRKMT2A | |
| SCHEMBL15186954 | 0.77 | PNPLA2 (1.00) | PNPLA2HDAC6TSHRKMT2A | |
| Fenuron SCHEMBL6304636 | 0.76 | TSHR (0.56) | TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |