Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 15/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14761353 | 0.79 | PRF1 (0.62) | PRF1LMNAALDH1A1MAPTGAA | |
| SCHEMBL16573996 | 0.78 | PRF1 (0.61) | PRF1LMNAALDH1A1MAPTGAA | |
| SCHEMBL13680699 | 0.77 | HSD17B1 (0.51) | — | |
| SCHEMBL2042246 | 0.76 | PRF1 (0.49) | PRF1LMNAALDH1A1MAPTGAA | |
| SCHEMBL13680985 | 0.75 | PRF1 (0.52) | PRF1LMNAMAPTGAAACHE | |
| SCHEMBL13680546 | 0.75 | PRF1 (0.58) | PRF1LMNAALDH1A1MAPTGAA | |
| SCHEMBL13680593 | 0.75 | CLK4 (0.56) | PRF1 | |
| SCHEMBL13469961 | 0.74 | PRF1 (0.65) | PRF1LMNAMAPTGAAACHE | |
| SCHEMBL6995518 | 0.73 | LMNA (0.62) | PRF1LMNAALDH1A1MAPTGAA | |
| SCHEMBL22643257 | 0.73 | PRF1 (0.55) | PRF1LMNAALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |